Sepsis (secretion) is an acute systemic infection caused by various pathogens invading the bloodstream, multiplying in the blood, and producing toxins. The factors that cause sepsis are as follows:

Sepsis is a serious disease. Statistics show that approximately 5 million new cases of sepsis are diagnosed in my country each year, with up to 1 million deaths, making it a leading cause of death among non-cardiac patients in intensive care units.

The systemic inflammation caused by sepsis can lead to acute brain dysfunction, manifesting as delirium, coma, and cognitive impairment. Nearly half of sepsis patients develop brain sequelae. While the survival rate of sepsis patients is increasing with advancements in medical technology, improving cognitive impairment among sepsis survivors remains a key research topic in the medical field.

Based on the fact that systemic inflammation is a key characteristic of sepsis, and that hydrogen molecules have anti-inflammatory and antioxidant mechanisms, a research team at the University of São Paulo, Brazil's top university, has twice attempted to use hydrogen inhalation to improve cognitive impairment in sepsis patients.